Journal article
Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
Abstract
BACKGROUND: Statin therapy has been shown to reduce major vascular events and vascular mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety among older people. We undertook a meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages.
METHODS: In this meta-analysis, randomised trials of statin therapy were eligible if they aimed to recruit at least …
Authors
Collaboration CTT; Armitage J; Baigent C; Barnes E; Betteridge DJ; Blackwell L; Blazing M; Bowman L; Braunwald E; Byington R
Journal
The Lancet, Vol. 393, No. 10170, pp. 407–415
Publisher
Elsevier
Publication Date
2 2019
DOI
10.1016/s0140-6736(18)31942-1
ISSN
0140-6736