Journal article
Changes in Phospholipid Extractability and Composition Accompany Mineralization of Chicken Growth Plate Cartilage Matrix Vesicles*
Abstract
Matrix vesicles are lipid bilayer-enclosed structures that initiate extracellular mineral formation. Little attention has been given to how newly formed mineral interacts with the lipid constituents and then emerges from the lumen. To explore whether specific lipids bind to the incipient mineral and if breakdown of the membrane is involved, we analyzed changes in lipid composition and extractability during vesicle-induced calcification. …
Authors
Wu LNY; Genge BR; Kang MW; Arsenault AL; Wuthier RE
Journal
Journal of Biological Chemistry, Vol. 277, No. 7, pp. 5126–5133
Publisher
Elsevier
Publication Date
February 2002
DOI
10.1074/jbc.m107899200
ISSN
0021-9258