Journal article
Taxol (paclitaxel) involution of articular cartilage destruction in collagen induced arthritis: an ultrastructural demonstration of an increased superficial chondroprotective layer.
Abstract
OBJECTIVE: To determine the ultastructural changes of Taxol (paclitaxel) involution of articular cartilage destruction in collagen induced arthritis (CIA) and to compare with articular cartilage from normal rats.
METHODS: Forty-five Louvain rats were randomized to one of 3 protocols for structural analysis: (1) control group, (2) CIA group, and (3) Taxol treated CIA group. The latter group received 10 mg/kg body weight of Taxol at Days 10, 12, …
Authors
Arsenault AL; Lhotak S; Hunter WL; Banquerigo ML; Brahn E
Journal
The Journal of Rheumatology, Vol. 27, No. 3, pp. 582–588
Publication Date
March 2000
ISSN
0315-162X