Journal article
Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial
Abstract
BACKGROUND: Tranexamic acid reduces blood loss and transfusion requirements in cardiac surgery but may increase the risk of coronary graft thrombosis. We previously reported the 30-day results of a trial evaluating tranexamic acid for coronary artery surgery. Here we report the 1-year clinical outcomes.
METHODS: Using a factorial design, we randomly assigned patients undergoing coronary artery surgery to receive aspirin or placebo and …
Authors
Myles PS; Smith JA; Kasza J; Silbert B; Jayarajah M; Painter T; Cooper DJ; Marasco S; McNeil J; Bussières JS
Journal
Journal of Thoracic and Cardiovascular Surgery, Vol. 157, No. 2, pp. 644–652.e9
Publisher
Elsevier
Publication Date
February 2019
DOI
10.1016/j.jtcvs.2018.09.113
ISSN
0022-5223
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Activities of Daily LivingAgedAntifibrinolytic AgentsAspirinCoronary Artery BypassCoronary Artery DiseaseCoronary ThrombosisDisability EvaluationDouble-Blind MethodFemaleFibrinolytic AgentsHemorrhageHumansMaleMiddle AgedMyocardial InfarctionProgression-Free SurvivalRisk FactorsTime FactorsTranexamic Acid