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An Empirical Comparison of Meta- and Mega-Analysis...
Journal article

An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group

Abstract

Objective: Brain imaging communities focusing on different diseases have increasingly started to collaborate and to pool data to perform well-powered meta- and mega-analyses. Some methodologists claim that a one-stage individual-participant data (IPD) mega-analysis can be superior to a two-stage aggregated data meta-analysis, since more detailed computations can be performed in a mega-analysis. Before definitive conclusions regarding the …

Authors

Boedhoe PSW; Heymans MW; Schmaal L; Abe Y; Alonso P; Ameis SH; Anticevic A; Arnold PD; Batistuzzo MC; Benedetti F

Journal

Frontiers in Neuroinformatics, Vol. 12, ,

Publisher

Frontiers

DOI

10.3389/fninf.2018.00102

ISSN

1662-5196