Silicosis, Radon, and Lung Cancer Risk in Ontario Miners

The presence of radiographic silicosis was assessed as a risk factor for lung cancer in a cohort and case-control study of miners in the Ontario Silicosis Surveillance Database. Subjects were 328 miners with silicosis matched on age to 970 miners with normal radiographs. In a cancer incidence follow-up, there was a significant excess of lung cancer among miners with silicosis (Standardized Incidence Ratio 2.55; 95% Confidence Interval …