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The effect of acetylsalicylic acid and...
Journal article

The effect of acetylsalicylic acid and indomethacin on rabbit platelet adherence to collagen and the subendothelium in the presence of a low or high hematocrit

Abstract

We have examined the effect of ASA and indomethacin on rabbit platelet adherence to collagen or the subendothelium over a range of hematocrits. Platelet adherence to the surfaces was measured in vitro using a rotating probe. Washed rabbit platelets were prelabeled with 51Cr and resuspended in media containing 4% albumin, apyrase and physiological concentrations of calcium and magnesium. ASA, indomethacin or their solvents were incubated for 10 …

Authors

Cazenave J-P; Kinlough-Rathbone RL; Packham MA; Mustard JF

Journal

Thrombosis Research, Vol. 13, No. 6, pp. 971–981

Publisher

Elsevier

Publication Date

December 1978

DOI

10.1016/0049-3848(78)90226-8

ISSN

0049-3848