In vitro effects of melatonin on HCG stimulation...

In vitro effects of melatonin on HCG stimulation of steroid accumulation by rabbit ovarian follicles

Abstract

Isolated rabbit ovarian follicles were incubated with HCG and/or melatonin, serotonin, 5-hydroxy-dl-tryptophan or N-acetyl serotonin. Melatonin alone significantly decreased the accumulation of steroids elicited by HCG stimulation. Follicles did not bind labelled melatonin whereas the specific binding of [125I]-HCG was 4.11 pmol per mg protein.

Authors

YoungLai EV

Journal

The Journal of Steroid Biochemistry and Molecular Biology, Vol. 10, No. 6, pp. 714–715

Publisher

Elsevier

Publication Date

January 1, 1979

DOI

10.1016/0022-4731(79)90528-4

ISSN

0960-0760

Associated Experts

Edward Younglai

Professor Emeritus, Faculty of Health Sciences

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