Thrombosis and atherosclerosis: The organization of pulmonary thromboemboli in the pig Macroscopic observations, protein, DNA, and major lipids

In order to investigate the possible contribution of the lipids of organizing thrombi to those of atherosclerotic plaques, the organization of autologous pulmonary thromboemboli in 8–12 week old Yorkshire pigs was studied at intervals from 6 hours to 4 weeks. Thrombi were prepared in vitro in Chandler rotating loops.There was a considerable loss of protein and total lipid in the interval from 6 hours to 5 days. No subsequent total lipid …