Journal article
A genome-wide linkage and association scan reveals novel loci for autism
Abstract
Scanning for links to autismAutism is a highly heritable neurodevelopmental disorder, and yet very few specific susceptibility genes have been identified to date. A genome-wide scan using half a million genome-wide SNPs (single nucleotide polymorphisms) in a common set of 1,031 multiplex autism families has now revealed significant linkage and association to autism. The linkage regions identified provide targets for rare variation screening …
Authors
Daly MJ; Chakravarti A; Arking DE; Brune CW; West K; O’Connor A; Hilton G; Tomlinson RL; West AB; Cook Jr EH
Journal
Nature, Vol. 461, No. 7265, pp. 802–808
Publisher
Springer Nature
Publication Date
10 2009
DOI
10.1038/nature08490
ISSN
0028-0836