Journal article
Identification and characterization of high-affinity Ca2+-ATPase associated with axonal plasma membranes of dog mesenteric nerves
Abstract
The microsomal fraction isolated from dog mesenteric nerve fibres was found to contain ATPase activity stimulated by micromolar concentrations of Ca ions. Such a high-affinity Ca2+-ATPase (hereafter referred to as HA Ca-ATPase) followed a Michaelis-Menten kinetics with Km for Ca ions of 0.4 μM and Vmax=12.5±2.4 μmol Pi.mg−1h−1. The examination of the subcellular origin of HA Ca-ATPase revealed that this enzyme is associated with axonal plasma …
Authors
Kostka P; Barnett WH; Kwan C-Y
Journal
Neurochemical Research, Vol. 15, No. 8, pp. 833–841
Publisher
Springer Nature
Publication Date
August 1990
DOI
10.1007/bf00968562
ISSN
0364-3190