Journal article
Neuromuscular blocking activity of two fractions isolated from the venom of the seasnake, Laticauda semifasciata
Abstract
Two components (0·06 M and 0·09 M fractions) have been isolated from the venom of the seasnake, Laticauda semifasciata. Both are similar polypeptides, each with about 100 amino acids and a mol. wt of approximately 10,000. When tested on the isolated chick biventer cervicis nerve-muscle preparation, both fractions were post-junctional cholinoceptor antagonists, although about 100 times less active than erabutoxin b from the same venom. The …
Authors
Harvey AL; Rodger IW; Tamiya N
Journal
Toxicon, Vol. 16, No. 1, pp. 45–50
Publisher
Elsevier
Publication Date
January 1978
DOI
10.1016/0041-0101(78)90059-4
ISSN
0041-0101