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Fluorescent Nanorods and Nanospheres for Real‐Time...
Journal article

Fluorescent Nanorods and Nanospheres for Real‐Time In Vivo Probing of Nanoparticle Shape‐Dependent Tumor Penetration

Abstract

Shape dependent: Fluorescent quantum‐dot‐based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real‐time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half‐life.

Authors

Chauhan VP; Popović Z; Chen O; Cui J; Fukumura D; Bawendi MG; Jain RK

Journal

Angewandte Chemie International Edition, Vol. 50, No. 48, pp. 11417–11420

Publisher

Wiley

Publication Date

November 25, 2011

DOI

10.1002/anie.201104449

ISSN

1433-7851

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