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Producing Covalent Microarrays of Amine‐Conjugated...
Journal article

Producing Covalent Microarrays of Amine‐Conjugated DNA Probes on Various Functional Surfaces to Create Stable and Reliable Biosensors

Abstract

Abstract Oligonucleotide‐based microarrays are ideal tools for genetic testing and diagnostics due to their stability, ease of synthesis, and high specificity for the target of interest. This study reports on the effectiveness of several coupling strategies to covalently attach single‐stranded nucleic acids to surfaces, focusing on the robustness of the attachment in various environmental conditions, such as pH and temperature. Various …

Authors

Yousefi H; Su H; Ali M; Filipe CDM; Didar TF

Journal

Advanced Materials Interfaces, Vol. 5, No. 16,

Publisher

Wiley

Publication Date

August 2018

DOI

10.1002/admi.201800659

ISSN

2196-7350