Journal article
Continuous flow microreactor for protein PEGylation
Abstract
PEGylation is increasingly being utilized to enhance the therapeutic efficacy of biopharmaceuticals. Various chemistries and reaction conditions have been established to synthesize PEGylated proteins and more are being developed. Both the extent of conversion and selectivity of protein PEGylation are highly sensitive to process variables and parameters. Therefore, microfluidic-based high-throughput screening platforms would be highly suitable …
Authors
Madadkar P; Selvaganapathy PR; Ghosh R
Journal
Biomicrofluidics, Vol. 12, No. 4,
Publisher
AIP Publishing
Publication Date
July 1, 2018
DOI
10.1063/1.5030984
ISSN
1932-1058