Ultrasmall superparamagnetic iron oxide to enhance MRA of the renal and coronary arteries: studies in human patients.

OBJECTIVE: Our goal was to determine the feasibility of using an intravascular MR contrast agent to improve 3D MRA. MATERIALS AND METHODS: Three-dimensional TOF MRA was performed in nine patients both prior to and following the administration of an ultrasmall particle superparamagnetic iron oxide contrast agent (AMI 227). The lengths of both renal arteries were measured from the maximum intensity projection (MIP) images as well as the …