Functional Magnetic Resonance Imaging of the Basal Ganglia and Cerebellum Using a Simple Motor Paradigm Academic Article uri icon

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abstract

  • Activation of cortical and subcortical motor areas of the brain, including primary motor cortex, supplementary motor area, basal ganglia and cerebellum, were successfully investigated in seven right-handed, normal volunteers during a simple, rapid, thumb flexion-extension task using functional magnetic resonance imaging. A multi-slice echo-planar imaging sequence was used to cover the entire brain. A signal increase varying from 2% to 6% was observed for the different regions involved in the motor task. Moving the non-dominant thumb was associated with a more bilateral activation pattern in both putamen and cerebellar regions. This study demonstrates the capability of functional magnetic resonance imaging to delineate simultaneously many activated brain areas that are commonly thought to be involved in the performance of motor tasks.

authors

  • Reichenbach, Jürgen R
  • Feiwell, Robert
  • Kuppusamy, Karthikeyan
  • Bahn, Mark
  • Haacke, Mark

publication date

  • April 1998

has subject area