The stability of proton T2 effects of oxygen‐17 water in experimental cerebral ischemia Journal Articles uri icon

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abstract

  • AbstractThe gerbil model of unilateral cerebral ischemia has been used to test the temporal and spatial stability of the MRI T2 effects of oxygen‐17 water. Following unilateral carotid ligation, symptomatic animals were given a single large intraperitoneal injection of H2 17O and the distribution and stability of the brain T2 effects were followed with a spin‐echo sequence. In contrast to the ischemic areas, the perfused tissue shows a marked and prolonged loss in intensity with little evidence of diffusion of the T2 effect of 17O into the ischemic tissue. © 1991 Academic Press, Inc.

authors

  • Hopkins, AL
  • Lust, WD
  • Haacke, Mark
  • Wielopolski, P
  • Barr, RG
  • Bratton, CB

publication date

  • November 1991