Predicting BOLD signal changes as a function of blood volume fraction and resolution

The appropriate choice of resolution in fMRI remains an open question. To address this issue, we simulate the signal change between activated and resting states as a function of blood volume fraction (lambda). From these results, the relative contrast-to-noise ratio (CNR) from the resting to the activated state can be calculated as a function of resolution. We consider different vessel orientations and note that, in most cases, the most …