Journal article
Rationale, design, and baseline participant characteristics in the MRI and cognitive substudy of the cardiovascular outcomes for people using anticoagulation strategies trial
Abstract
BACKGROUND: Covert vascular disease of the brain manifests as infarcts, white matter hyperintensities, and microbleeds on MRI. Their cumulative effect is often a decline in cognition, motor impairment, and psychiatric disorders. Preventive therapies for covert brain ischemia have not been established but represent a huge unmet clinical need.
AIMS: The MRI substudy examines the effects of the antithrombotic regimens in COMPASS on incident covert …
Authors
Sharma M; Hart RG; Smith EE; Bosch J; Yuan F; Casanova A; Eikelboom JW; Connolly SJ; Wong G; Diaz R
Journal
International Journal of Stroke, Vol. 14, No. 3, pp. 270–281
Publisher
SAGE Publications
Publication Date
4 2019
DOI
10.1177/1747493018784478
ISSN
1747-4930