Mosaic Hydrogels: One‐Step Formation of Multiscale Soft Materials Journal Articles uri icon

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  • The one-step, continuous formation of mosaic hydrogel sheets is presented. A microfluidic device allows controllable incorporation of secondary biopolymers within a flowing biopolymer sheet followed by a cross-linking step that retains the microscale composition. Information is encoded; mosaic stiffness and diffusivity patterns are created; tessellations are populated with biomolecules, microparticles and viable primary cells; and 3D soft material assemblies are demonstrated.


  • Leng, Lian
  • McAllister, Arianna
  • Zhang, Boyang
  • Radisic, Milica
  • Günther, Axel

publication date

  • July 17, 2012