Journal article
Mosaic Hydrogels: One‐Step Formation of Multiscale Soft Materials
Abstract
The one-step, continuous formation of mosaic hydrogel sheets is presented. A microfluidic device allows controllable incorporation of secondary biopolymers within a flowing biopolymer sheet followed by a cross-linking step that retains the microscale composition. Information is encoded; mosaic stiffness and diffusivity patterns are created; tessellations are populated with biomolecules, microparticles and viable primary cells; and 3D soft …
Authors
Leng L; McAllister A; Zhang B; Radisic M; Günther A
Journal
Advanced Materials, Vol. 24, No. 27, pp. 3650–3658
Publisher
Wiley
Publication Date
July 17, 2012
DOI
10.1002/adma.201201442
ISSN
0935-9648