Journal article
Ultrastructure of Bone: Hierarchical Features from Nanometer to Micrometer Scale Revealed in Focused Ion Beam Sections in the TEM
Abstract
The ultrastructure of bone has been widely debated, in part due to limitations in visualizing nanostructural features over relevant micrometer length scales. Here, we employ the high resolving power and compositional contrast of high-angle annular dark-field scanning transmission electron microscopy (HAADF STEM) to investigate new features in human bone with nanometer resolution over microscale areas. Using focused ion beam (FIB)-milled …
Authors
Grandfield K; Vuong V; Schwarcz HP
Journal
Calcified Tissue International, Vol. 103, No. 6, pp. 606–616
Publisher
Springer Nature
Publication Date
12 2018
DOI
10.1007/s00223-018-0454-9
ISSN
0171-967X