Journal article
The effect of melatonin on sleep and quality of life in patients with advanced breast cancer
Abstract
BackgroundFatigue and sleep problems are prevalent in cancer patients and can be associated with disruption of circadian rhythmicity. In this prospective phase II trial, we sought to assess the effect of melatonin on circadian biomarkers, sleep, and quality of life in breast cancer patients.MethodsThirty-two patients with metastatic breast cancer, receiving hormonal or trastuzumab therapy, took 5 mg of melatonin at bedtime for 2 months. Before …
Authors
Innominato PF; Lim AS; Palesh O; Clemons M; Trudeau M; Eisen A; Wang C; Kiss A; Pritchard KI; Bjarnason GA
Journal
Supportive Care in Cancer, Vol. 24, No. 3, pp. 1097–1105
Publisher
Springer Nature
Publication Date
March 2016
DOI
10.1007/s00520-015-2883-6
ISSN
0941-4355