Journal article
Prevention of anti‐inflammatory drug‐induced gastrointestinal damage: Benefits and risks of therapeutic strategies
Abstract
Patients who take non-steroidal anti-inflammatory drugs (NSAIDs) may develop serious gastrointestinal (GI) side effects in both the upper and lower GI tract. Those at risk should be considered for prevention with misoprostol, proton pump inhibitor (PPI) or COX-2 selective inhibitor (coxib) therapy. A coxib or an NSAID+PPI combination is considered to have comparable GI safety profiles, but evidence from direct comparison is limited. PPIs are …
Authors
Lanas A; Hunt R
Journal
Annals of Medicine, Vol. 38, No. 6, pp. 415–428
Publisher
Taylor & Francis
Publication Date
January 2006
DOI
10.1080/07853890600925843
ISSN
0785-3890