Journal article
Cell Line-Specific Direct Irradiation and Bystander Responses are Influenced by Fetal Bovine Serum Serotonin Concentrations
Abstract
The radiation-induced bystander effect is mechanistically complex, involving many different signaling components. Serotonin, present in fetal bovine serum (FBS), has been implicated in the modulation of cellular responses to radiation. However, the role of this ubiquitous signaling molecule has yet to be elucidated with regard to cell line-specific radiation responses. In this study, cell survival was measured in HCT116 p53 wild-type (HCT116+/+)…
Authors
Curtis JJ; Seymour CB; Mothersill CE
Journal
Radiation Research, Vol. 190, No. 3, pp. 262–270
Publisher
Radiation Research Society
Publication Date
September 2018
DOI
10.1667/rr15072.1
ISSN
0033-7587