Smokers and Postcessation Weight Gain After Acute Coronary Syndrome Journal Articles

abstract

• Background Smoking cessation and weight management are recommended after acute coronary syndrome ( ACS ); however, little is known about the effects of smoking cessation on weight change after ACS . We aimed to assess the effect of smoking cessation after ACS on weight over a 12‐month follow‐up period. Methods and Results Data were prospectively collected from the EVITA (Evaluation of Varenicline in Smoking Cessation for Patients Post‐Acute Coronary Syndrome) trial. Weight change was compared among 3 groups of patients: those who were completely abstinent (n=70), those who smoked intermittently (n=68), and those who smoked persistently (n=34). Patients' mean baseline weight was 83.9 kg ( SD 17.7) with a mean body mass index of 28.5 ( SD 5.4). Patients smoked a mean of 37.7 years ( SD 17.7) and a mean of 21.0 cigarettes ( SD 9.0) per day prior to their ACS . Weight change varied across groups, with abstainers gaining a mean of 4.8 kg ( SD 8.6), intermittent smokers gaining a mean of 2.0 kg ( SD 8.9) and persistent smokers losing a mean of 0.7 kg ( SD 7.4). At 52 weeks, abstainers were more likely to gain weight than persistent smokers (difference in means 5.5 kg; 95% CI 2.3–8.8). This weight gain was not associated with an increase in the use of antihypertensive or antidiabetic medications. Conclusions Following an ACS , significant weight is gained by patients who quit smoking. Weight‐management interventions among smokers who quit after ACS should be a focus of investigation in future research so that the cardiovascular benefits achieved by smoking cessation are not offset by weight gain in this high‐risk population. Clinical Trial Registration URL : http://www.clinicaltrials.gov . Unique identifier: NCT 00794573.

authors

• Dehghani, Payam
• Habib, Bettina
• Windle, Sarah B
• Roy, Nathalie
• Old, Wayne
• Grondin, François R
• Bata, Iqbal
• Iskander, Ayman
• Lauzon, Claude
• Srivastava, Nalin
• Clarke, Adam
• Cassavar, Daniel
• Dion, Danielle
• Haught, Herbert
• Mehta, Shamir
• Baril, Jean‐François
• Lambert, Charles
• Madan, Mina
• Abramson, Beth L
• Eisenberg, Mark J

status

• published 

publication date

• April 5, 2017

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• Acute Coronary Syndrome (MeSH)
• Aged (MeSH)
• Blood Pressure (MeSH)
• Body Mass Index (MeSH)
• Double-Blind Method (MeSH)
• Female (MeSH)
• Humans (MeSH)
• Male (MeSH)
• Middle Aged (MeSH)
• Nicotinic Agonists (MeSH)
• Prospective Studies (MeSH)
• Recurrence (MeSH)
• Risk Factors (MeSH)
• Risk Reduction Behavior (MeSH)
• Smoking (MeSH)
• Smoking Cessation (MeSH)
• Smoking Prevention (MeSH)
• Time Factors (MeSH)
• Tobacco Use Cessation Devices (MeSH)
• Treatment Outcome (MeSH)
• Varenicline (MeSH)
• Weight Gain (MeSH)

published in

• Journal of the American Heart Association  Journal

keywords

• Acute Coronary Syndrome
• Aged
• Blood Pressure
• Body Mass Index
• Double-Blind Method
• Female
• Humans
• Male
• Middle Aged
• Nicotinic Agonists
• Prospective Studies
• Recurrence
• Risk Factors
• Risk Reduction Behavior
• Smoking
• Smoking Cessation
• Smoking Prevention
• Time Factors
• Tobacco Use Cessation Devices
• Treatment Outcome
• Varenicline
• Weight Gain
• acute coronary syndrome
• secondary prevention
• smoking
• weight gain

Digital Object Identifier (DOI)

• 10.1161/jaha.116.004785

start page

• e004785

volume

• 6

issue

• 4