Journal article
Novel Oral Anticoagulants and the Risk of Major Hemorrhage in Elderly Patients With Chronic Kidney Disease: A Nested Case-Control Study
Abstract
BACKGROUND: The novel oral anticoagulants, including dabigatran and rivaroxaban, differ in their degree of renal excretion.
METHODS: We conducted a population-based nested case-control study in patients 66 years and older with chronic kidney disease (CKD) (excluding patients undergoing chronic dialysis) who received an oral anticoagulant between April 2006 and March 2013. We calculated odds ratios for hospitalization with a major hemorrhagic …
Authors
Harel Z; Mamdani M; Juurlink DN; Garg AX; Wald R; Yao Z; Gomes T
Journal
Canadian Journal of Cardiology, Vol. 32, No. 8, pp. 986.e17–986.e22
Publisher
Elsevier
Publication Date
August 2016
DOI
10.1016/j.cjca.2016.01.013
ISSN
0828-282X