Journal article
Trimethoprim-sulfamethoxazole induced hyperkalaemia in elderly patients receiving spironolactone: nested case-control study
Abstract
OBJECTIVES: To characterise the risk of admission to hospital for hyperkalaemia in elderly patients treated with trimethoprim-sulfamethoxazole in combination with spironolactone.
DESIGN: Population based nested case-control study.
Authors
Antoniou T; Gomes T; Mamdani MM; Yao Z; Hellings C; Garg AX; Weir MA; Juurlink DN
Journal
The BMJ, Vol. 343, No. sep12 1,
Publisher
BMJ
Publication Date
September 12, 2011
DOI
10.1136/bmj.d5228
ISSN
0959-8138
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedAged, 80 and overAmoxicillinAnti-Infective Agents, UrinaryCase-Control StudiesDrug InteractionsDrug Therapy, CombinationFemaleHumansHyperkalemiaLogistic ModelsMaleMineralocorticoid Receptor AntagonistsNitrofurantoinNorfloxacinOdds RatioOntarioPatient AdmissionRiskSpironolactoneTrimethoprim, Sulfamethoxazole Drug Combination