Endocrine Disruptors and Development of the Reproductive System in the Fetus and Children: Is There Cause for Concern?

Reports of decreased semen quality and increased rates of developmental abnormalities of the male reproductive tract along with increasing incidence of testicular cancer have focused attention on man-made chemicals as potential causative factors. A biologically plausible hypothesis has been advanced which suggests that man-made chemicals act as endocrine disruptors through interaction with the estrogen receptor resulting in altered development …