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Immunoglobulin-mediated hypersensitivity in...
Journal article

Immunoglobulin-mediated hypersensitivity in response to long-term treatment with gonadorelin hydrochloride (Factrel) in a female patient

Abstract

Recently a patient with severe hypogonadotropic hypogonadism who was given luteinizing hormone-releasing hormone (Factrel) through an infusion pump developed a wheat-and-flare reaction at the sites of injection. Treatment with luteinizing hormone-releasing hormone was discontinued and the immune response was characterized. Skin testing by skin prick test was positive for luteinizing hormone-releasing hormone but negative for vehicle. …

Authors

Foster WG; Jarrell JF; Dolovich J; YoungLai EV

Journal

American Journal of Obstetrics and Gynecology, Vol. 160, No. 4, pp. 979–983

Publisher

Elsevier

Publication Date

April 1989

DOI

10.1016/0002-9378(89)90320-7

ISSN

0002-9378