Journal article
Bisphenol A concentration-dependently increases human granulosa-lutein cell matrix metalloproteinase-9 (MMP-9) enzyme output
Abstract
Bisphenol A (BPA) is an estrogenic contaminant that has been quantified at higher levels in the follicular fluid of women with polycystic ovarian syndrome (PCOS) compared to healthy fertile controls. However, the effect of BPA on granulosa cell function is unknown. Therefore, the objective of the present study was to quantify the effect of BPA on granulosa cell progesterone (P4) output and matrix metalloproteinase (MMP)-2, and -9 output and …
Authors
Dominguez MA; Petre MA; Neal MS; Foster WG
Journal
Reproductive Toxicology, Vol. 25, No. 4, pp. 420–425
Publisher
Elsevier
Publication Date
August 2008
DOI
10.1016/j.reprotox.2008.05.059
ISSN
0890-6238