Journal article
Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa receptor-directed platelet inhibition
Abstract
BACKGROUND: Platelet surface glycoprotein IIb/IIIa (alphaIIb/beta3) receptor inhibition, with prevention of fibrinogen binding and platelet aggregation, concomitantly attenuates arterial thrombotic capacity and impairs protective hemostasis, 2 divergent platelet-dependent processes.
PURPOSE: Because the currently available, Food and Drug Administration-approved small molecule glycoprotein IIb/IIIa receptor antagonists are considered …
Authors
Li YF; Spencer FA; Becker RC
Journal
American Heart Journal, Vol. 143, No. 4, pp. 725–732
Publisher
Elsevier
Publication Date
4 2002
DOI
10.1067/mhj.2002.120299
ISSN
0002-8703