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Comparative Effects of Unfractionated Heparin and...
Journal article

Comparative Effects of Unfractionated Heparin and Low Molecular Weight Heparin on Vascular Endothelial Cell Tissue Factor Pathway Inhibitor Release: A Model for Assessing Intrinsic Thromboresistance

Abstract

Objectives: The purpose of our study was to characterize tissue factor pathway inhibitor (TFPI) release from human vascular endothelial cells following daily exposure to varying concentrations of unfractionated heparin (UFH) and low molecular weight heparin (LMWH).Background: A “rebound” increase in ischemic/thrombotic events, including myocardial infarction and cardiovascular death, has been observed after the abrupt cessation of UFH. In a …

Authors

Li Y; Rodriquez M; Spencer FA; Becker RC

Journal

Journal of Thrombosis and Thrombolysis, Vol. 14, No. 2, pp. 123–129

Publisher

Springer Nature

Publication Date

October 2002

DOI

10.1023/a:1023280811804

ISSN

0929-5305