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Fetal Exposure to Sertraline Hydrochloride Impairs...
Journal article

Fetal Exposure to Sertraline Hydrochloride Impairs Pancreatic β-Cell Development

Abstract

Ten percent to 15% of women take selective serotonin reuptake inhibitor (SSRI) antidepressants during pregnancy. Offspring exposed to SSRIs are more likely to have low birth weight; this is associated with an increased risk of development of diabetes in adulthood in part due to altered pancreatic development. The effects of perinatal exposure to SSRIs on pancreatic development are unknown. Therefore, the objective of this study was to determine …

Authors

De Long NE; Gutgesell MK; Petrik JJ; Holloway AC

Journal

Endocrinology, Vol. 156, No. 6, pp. 1952–1957

Publisher

The Endocrine Society

Publication Date

June 1, 2015

DOI

10.1210/en.2014-1779

ISSN

0013-7227