Developmental Care for Very Low-Birth-Weight Infants

To the Editor. —Although it is laudable that Dr Als and colleagues1 have evaluated a difficult issue such as developmental care in very low-birth-weight infants in a randomized controlled trial, we would like to point out certain methodological concerns. First, considering the large size of the unit, the 43 subjects enrolled over a 21-month period may represent a small and highly select group of the overall admissions, thus diminishing the …