Changes in the perception of inspiratory resistive loads during partial curarization.

1. The ability of normal subjects to estimate the magnitude of resistive loads and to detect resistive loads was determined using standard psychophysical techniques. The experiments were repeated during maintained partial neuromuscular blockade with D-tubocurarine. 2. During curarization the ability to detect the presence of a small inspiratory resistive load was not significantly impaired. This finding is consistent with the view that changes …