Continuous Glucose Monitoring in Pregnant Women With Type 1 Diabetes (CONCEPTT): A Multicenter International Randomised Controlled Trial Journal Articles uri icon

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  • (Abstracted from Lancet 2017;390:2347–2359) It is established that optimal maternal glycemic control throughout pregnancy is associated with a decrease in adverse fetal outcomes. A proper glycemic index can be difficult to control in women with type 1 diabetes during pregnancy because of the complexity of insulin dose adjustment, gestational changes in insulin sensitivity, and day-to-day changes to insulin absorption in late pregnancy. Nationwide UK data show the rates of severe hypoglycemia, particularly in early pregnancy, are 5 times higher among pregnant women than nonpregnant and that only 40% of women with type 1 diabetes achieve target glycated hemoglobin (HbA1c) after 24 weeks of gestation. Continuous glucose monitoring (CGM) provides real-time quantitative information on the direction and rate of change of glucose levels.


  • Feig, Denice S
  • Donovan, Lois E
  • Corcoy, Rosa
  • Murphy, Kellie E
  • Amiel, Stephanie A
  • Hunt, Katharine F
  • Asztalos, Elizabeth
  • Barrett, Jon FR
  • Sanchez, J Johanna
  • de Leiva, Alberto
  • Hod, Moshe
  • Jovanovic, Lois
  • Keely, Erin
  • McManus, Ruth
  • Hutton, Eileen Katherine
  • Meek, Claire L
  • Stewart, Zoe A
  • Wysocki, Tim
  • O'Brien, Robert
  • Ruedy, Katrina
  • Kollman, Craig
  • Tomlinson, George
  • Murphy, Helen R

publication date

  • April 2018