“PSA-itis”: Knowledge of Serum Prostate Specific Antigen and Other Causes of Anxiety in Men with Metastatic Prostate Cancer

PURPOSE: High or increasing prostatic specific antigen (PSA) levels may be a source of anxiety in patients with metastatic prostate cancer. MATERIALS AND METHODS: Patients with metastatic prostate cancer completed questionnaires, including the Prostate Cancer Specific Quality of Life Instrument, Hospital Anxiety and Depression Scale, and a questionnaire to assess the impact of the knowledge of PSA levels on anxiety. These were completed at home …