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The effect of homocysteine-lowering with...
Journal article

The effect of homocysteine-lowering with B-vitamins on osteoporotic fractures in patients with cerebrovascular disease: substudy of VITATOPS, a randomised placebo-controlled trial

Abstract

BackgroundHomocysteine has been postulated as a novel, potentially reversible risk factor for osteoporosis and related fractures. We evaluated whether homocysteine-lowering therapy with B-vitamins in patients with symptomatic cerebrovascular disease reduced the incidence of osteoporotic fractures.MethodsVITAmins To Prevent Stroke (VITATOPS) was a prospective randomised double-blind placebo-controlled trial in which 8,164 patients with recent …

Authors

Gommans J; Yi Q; Eikelboom JW; Hankey GJ; Chen C; Rodgers H

Journal

BMC Geriatrics, Vol. 13, No. 1,

Publisher

Springer Nature

Publication Date

12 2013

DOI

10.1186/1471-2318-13-88

ISSN

1471-2318