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Mortality and morbidity in acutely ill adults...
Journal article

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis

Abstract

BACKGROUND: Supplemental oxygen is often administered liberally to acutely ill adults, but the credibility of the evidence for this practice is unclear. We systematically reviewed the efficacy and safety of liberal versus conservative oxygen therapy in acutely ill adults. METHODS: In the Improving Oxygen Therapy in Acute-illness (IOTA) systematic review and meta-analysis, we searched the Cochrane Central Register of Controlled Trials, MEDLINE, …

Authors

Chu DK; Kim LH-Y; Young PJ; Zamiri N; Almenawer SA; Jaeschke R; Szczeklik W; Schünemann HJ; Neary JD; Alhazzani W

Journal

The Lancet, Vol. 391, No. 10131, pp. 1693–1705

Publisher

Elsevier

Publication Date

4 2018

DOI

10.1016/s0140-6736(18)30479-3

ISSN

0140-6736