Age sensitive associations of adolescent substance use with amygdalar, ventral striatum, and frontal volumes in young adulthood

INTRODUCTION: This study evaluated an age sensitive model of substance use across adolescence to determine if substance use was associated with smaller volumes for an earlier developing brain region, the amygdala, a later developing region, the inferior frontal gyrus, and the ventral striatum. METHOD: Participants (N = 110) were African American young adults who were members of a longitudinal cohort across childhood and adolescence. Measures of …