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Identification of the acid‐induced degradation...
Journal article

Identification of the acid‐induced degradation products of omeprazole and 5‐hydroxyomeprazole by high‐resolution mass spectrometry

Abstract

RATIONALE: Omeprazole is used to treat gastric disorders and is one of the most commonly consumed drugs in the western world. It forms several metabolites but is mostly excreted unchanged and as 5-hydroxyomeprazole. Since omeprazole is widely prescribed, its excretion from the body has a potential environmental effect. After excretion it will enter the wastewater system and if not adequately removed during wastewater treatment will be …

Authors

Roberts J; McNaughtan ML; MacLachlan J; Hunter C; Pahl O

Journal

Rapid Communications in Mass Spectrometry, Vol. 32, No. 12, pp. 929–941

Publisher

Wiley

Publication Date

June 30, 2018

DOI

10.1002/rcm.8120

ISSN

0951-4198