Journal article
Underestimation of Uncertainties in Health Utilities Derived from Mapping Algorithms Involving Health-Related Quality-of-Life Measures
Abstract
OBJECTIVES: Mapping algorithms are being developed in increasing numbers to derive health utilities (HUs) from health-related quality-of-life (HRQOL) data. However, the variances of the mapping-derived HUs are observed to be smaller than those of the actual HUs.
METHODS: Two reasons are proposed: 1) the presence of important unmeasured predictors leading to a high degree of unexplained variance and 2) ignoring that the regression coefficients …
Authors
Chan KKW; Willan AR; Gupta M; Pullenayegum E
Journal
Medical Decision Making, Vol. 34, No. 7, pp. 863–872
Publisher
SAGE Publications
Publication Date
10 2014
DOI
10.1177/0272989x13517750
ISSN
0272-989X