Journal article
Metronomic PDT and Cell Death Pathways
Abstract
The term “metronomic” was recently introduced to describe continuous low-dose administration of chemotherapeutics following the discovery that this causes minimal side effects (Hanahan et al. 2000, J Clin Invest, 105(8), 1045–1047; Bisland et al. 2004, Photochem Photobiol, 80, 22–30). Metronomic dosing in PDT is proposed by analogy and the rationale is as a means to improve the tumor-specific response through cell death by apoptosis. We …
Authors
Singh G; Alqawi O; Espiritu M
Journal
Methods in Molecular Biology, Vol. 635, , pp. 65–78
Publisher
Springer Nature
Publication Date
2010
DOI
10.1007/978-1-60761-697-9_5
ISSN
1064-3745