Journal article
Low expression of long-chain acyl-CoA dehydrogenase in human skeletal muscle
Abstract
PURPOSE: Long-chain acyl-CoA dehydrogenase (LCAD) is a mitochondrial flavoenzyme thought to be one of the major enzymes responsible for the first step of long-chain fatty acid (LCFA) beta-oxidation. Surprisingly, recent studies have shown LCAD is hardly detectable in human tissues such as liver and heart. Skeletal muscle is the largest organ in the body in terms of mass, and accounts for the majority of LCFA oxidation, especially during …
Authors
Maher AC; Mohsen A-W; Vockley J; Tarnopolsky MA
Journal
Molecular Genetics and Metabolism, Vol. 100, No. 2, pp. 163–167
Publisher
Elsevier
Publication Date
6 2010
DOI
10.1016/j.ymgme.2010.03.011
ISSN
1096-7192