The Novel Impact Of Treadmill Exercise And Sex Difference On Cell Proliferation and Cell Survival In The Dentate Gyrus Of G93A Mice

Neurogenesis persists in the adult mammalian brain and can be regulated by physiological stressors influencing cell proliferation or cell survival. We investigated whether sex and treadmill running would affect cell proliferation and newborn cell survival in the dentate gyrus (DG) of G93A mice, a transgenic model over‐expressing mutant human Cu/Zn‐superoxide dismutase (SOD1) and leading to excessive oxidative stress. Proliferating and surviving …