Conference
The effects of creatine and exercise on skeletal muscle of FRG1‐transgenic mice
Abstract
Transgenic overexpression of Fascioscapulohumeral Muscular Dystrophy (FSHD) Region Gene 1 (FRG1) results in severe muscle atrophy and weakness reminiscent of the human disease FSHD. Treatments that act to mitigate muscle dysfunction in the FRG1‐transgenic mouse could hold therapeutic benefit to FSHD patients. Forty FRG1 mice were divided into sedentary, creatine (Cr), and combination creatine and exercise treated groups (CrEx). Creatine was …
Authors
Ogborn DI; Safdar A; Hettinga BP; Crane JD; Tupler R; Tarnopolsky MA
Volume
24
Pagination
pp. 618.8-618.8
Publisher
Wiley
Publication Date
April 2010
DOI
10.1096/fasebj.24.1_supplement.618.8
Conference proceedings
The FASEB Journal
Issue
S1
ISSN
0892-6638