Conference
455 KETOCONAZOLE TREATMENT IN BOYS WITH PRECOCIOUS PUBERTY
Abstract
Three boys with familial gonadotropin-independent precocious puberty (Rosenthal et al,JCEM 57:571, 1983)were treated with LHRH analog for periods of 1–4 mos, without clinical or biochemical response. The effects of the antifungal drug ketoconazole were studied in these boys prompted by the observation that this agent may interfere with testosterone biosynthesis. With 200mg/12 h P.0. there was an immediate significant fall in serum …
Authors
Holland FJ; Fishman L; Bailey JD; Kooh SW
Volume
19
Pagination
pp. 186-186
Publisher
Springer Nature
Publication Date
4 1985
DOI
10.1203/00006450-198504000-00485
Conference proceedings
Pediatric Research
Issue
4
ISSN
0031-3998