Journal article
Sarcomas and the Immune System: Implications for Therapeutic Strategies
Abstract
Soft-tissue sarcomas are a heterogeneous group of tumors that are capable of generating host immune responses. Historically the role of antitumor immunity was first studied in soft-tissue sarcomas. Subsequent in vitro studies, preclinical models, and clinical observations have provided ample evidence for an immunologic approach to sarcoma treatment. Initial clinical trials involving vaccines and adoptive immunotherapy have demonstrated …
Authors
Francescutti V; Skitzki JJ
Journal
Surgical Oncology Clinics of North America, Vol. 21, No. 2, pp. 341–355
Publisher
Elsevier
Publication Date
April 2012
DOI
10.1016/j.soc.2011.11.002
ISSN
1055-3207