Journal article
Fluconazole non-susceptible breakthrough candidemia after prolonged low-dose prophylaxis: a prospective FUNGINOS study
Abstract
OBJECTIVES: Breakthrough candidemia (BTC) on fluconazole was associated with non-susceptible Candida spp. and increased mortality. This nationwide FUNGINOS study analyzed clinical and mycological BTC characteristics.
METHODS: A 3-year prospective study was conducted in 567 consecutive candidemias. Species identification and antifungal susceptibility testing (CLSI) were performed in the FUNGINOS reference laboratory. Data were analyzed according …
Authors
Orasch C; Mertz D; Garbino J; van Delden C; Emonet S; Schrenzel J; Zimmerli S; Damonti L; Mühlethaler K; Imhof A
Journal
Journal of Infection, Vol. 76, No. 5, pp. 489–495
Publisher
Elsevier
Publication Date
May 2018
DOI
10.1016/j.jinf.2017.12.018
ISSN
0163-4453